You can revisit last week's picks here.
The BCS will release it's first set of rankings this Sunday, so expect a lot of good play from teams auditioning for a place in the top 10.
That said, it's time to offer another round of picks.
(All lines are courtesy of VegasInsider.com).
1. Alabama vs. Ole Miss: Alabama (-20.5)
This actually seems like a ton of points to lend the Tide's way—even if they are playing in Tuscaloosa. That said, the Rebels aren't very good on defense.
Look for both Mark Ingram and Trent Richardson to get something they didn't last week—running room—and look for the Tide to take out their frustration on the Rebels.
The Lady's Pick: Alabama
2. Michigan vs. Iowa: Iowa (-3)
As impressive as Iowa has been all season, save the loss to Arizona in week three, Michigan's offense is going to be tough to stop at home. Sure Michigan State came in and shut Denard Robinson down, but the Spartans have played the Wolverines well over the last few seasons and that loss wasn't really all that hard to see coming.
That said, Iowa has been nearly as effective, defensively, on the road as they have been at home.
Expect Mr. Robinson to rebound and steal a win from the Hawkeye's.
The Lady's Pick: Michigan
3. Virginia Tech vs. Wake Forest: Virginia Tech (-22.5)
Wake Forest is atrocious, there is little doubt about that, but they have played a better brand of football over the last couple of weeks, and have nothing to lose by giving it all they've got against a Hokie squad that, honestly, still isn't all that impressive.
The Lady's Pick: Wake Forest
4. TCU vs BYU: TCU (-28)
TCU is good. BYU is bad. There is not much else you can say about these two teams or this match-up.
BYU's coach is currently wearing two hats (head coach and defensive coordinator) and that has to be tough, considering he's got a true freshman quarterback trying to run the offense.
The Cougars are a mess right now and, even though it seems crazy to think they will get beat by 28 points, that's what is likely to happen.
The Lady's Pick: TCU
5. Texas Tech vs. Oklahoma State: Texas Tech (-3.5)
Texas Tech is still trying to find themselves under Tommy Tuberville, and it's not clear that they are anywhere near close to doing that right now—despite their 3-2 record.
The Lady's Pick: Oklahoma State
6. Rice vs. Houston: Houston (-9)
As terrible as the defense of the Cougars is, the Owls might be worse. If Houston quarterbacks, David Piland or Terrance Broadway, want to get their respective games going, then this is the week to do it.
The Owls have little in the way of offense and don't defend well against the pass—a recipe for disaster when you're opponent specializes in air raids.
The Lady's Pick: Houston
7. Wisconsin vs. Ohio State: Ohio State (-4)
Hmmm, wonder what Bielema's card will tell him to do this week?
He better have a definite plan of action against the Buckeyes ,or he'll be the one feeling some kind of wronged after this game.
The Lady's Pick: Ohio State
8. Auburn vs. Arkansas: Auburn (-3.5)
Auburn has been getting by on the grace and talent of Cam Newton—no doubt about it. However, the cardiac cats will have to go into arrest at some point, and it's highly possible that the Razorbacks will be just the team to send them rushing for the nearest ambulance.
The Lady's Pick: Arkansas
9. Georgia Tech vs Middle Tennessee State: Georgia Tech (-19)
This pick could come back to haunt me later, but, Dwight Dasher could end up being a problem for that developing Yellow Jacket defense. He's much better than he showed last week, and this could be just the game he needs to get his game back on the right track.
Georgia Tech will definitely win, but not by 19.
The Lady's Pick: Middle Tennessee
10. Florida vs. Mississippi State: Florida (-9)
Mississippi State might be scrappy but their quarterback situation leaves much to be desired. Expect the Gators to get back to their winning ways this weekend.
The Lady's Pick: Florida
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